Under the name of Glubrim two efficient drugs are brought together, Brimonidine Tartrate and Timolol Maleate.

MODE OF ACTION- Both, Brimonidine tartrate and Timolol maleate have separate mechanism to control the ocular pressure and are discussed below-:

BRIMONIDINE TARTRATE stimulates alpha receptors found on the blood vessels that supply the ciliary body. This causes the blood vessels to constrict, and reduces the amount of watery fluid that filters out of the blood vessels to form aqueous humour. Brimonidine therefore works by reducing the inflow of aqueous humour into the eyeball, which decreases the pressure within the eye. It is used to treat conditions where there is raised pressure in the eye, such as glaucoma

TIMOLOL MALEATE is a beta blocker that enables the blocking of beta receptors present on cells of different muscles. As an ophthalmic solution it acts on the beta receptors of the ciliary epithelium of the eye and blocks the receptors responsible for the production of aqueous humor (increase in its production causes the increase of the intra ocular pressure resulting in Glaucoma), thus decreasing the pressure.

Ocular hypertension and Open angle glaucoma.

1. Ocular pressure should be monitored timely
2. If allergic discontinue the use and contact your eye doctor
3. Eye discomfort/itching/redness, blurred vision, dizziness, dry mouth, drowsiness, or tiredness may occur. If any of these effects persist or worsen, notify your eye doctor.