Tobramycin is widely administered amino glycoside antibiotic for ocular and Otic infections because of its efficiency to eliminating gram-negative bacteria especially pseudomonas species.

AS OPHTHALMIC: Tobramycin ophthalmic solution remains stable for several weeks in varied solutions with an ability to get absorbed in aqueous humor.

AS OTIC: In the form of ear drops Tobram is used to treat outer ear infections.

Mode of Action:

Tobramycin readily binds with the ribosomal pair disabling it to produce m-Rna responsible for the protein formation in bacteria thus ensuring cell death. It also destabilizes the bacterial membrane by binding the 16s r-Rna thus the functional integrity of the bacterial cell membrane appears to be disrupted.

Conjunctivitis, Blepharitis, pediatric ocular infections, post eye operation, ear canal infections and vision threatening bacterial infections.

• Indiscriminate and prolonged use may result in overgrowth of non susceptible organisms, including fungal infections, glaucoma and cataract.
• If irritation persists discontinue its usage and contact your physician.

Adverse Effect:

• Eye ointments usually cause your vision to blur for a few minutes after application
• May temporarily sting when first applied
• If allergic to the drug, symptoms include: rash, itching, redness, watery eyes and swelling.