Tobramycin is widely administered amino glycoside antibiotic for external infections of the eye and its adnexa because of its efficiency to eliminating gram-negative bacteria especially pseudomonas species. It is preferred due to its broad spectrum that covers strains resistant to gentamycin. Topically administered antibiotics used alone as well as with other drugs to kill bacteria.

Mode of Action:

Tobramycin readily binds with the ribosomal pair disabling it to produce m-RNA responsible for the protein formation in bacteria thus ensuring cell death. It also destabilizes the bacterial membrane by binding the 16s r- RNA thus the functional integrity of the bacterial cell membrane appears to be disrupted.

Conjunctivitis, Blepharitis, pediatric ocular infections, post eye operation and vision threatening bacterial infections.

• Indiscriminate and prolonged use may result in overgrowth of non susceptible organisms, including fungal infections, glaucoma and cataract.
• If irritation persists discontinue its usage and contact your physician.

Adverse Effect:

• Eye ointments usually cause your vision to blur for a few minutes after application
• May temporarily sting when first applied
• If allergic to the drug, symptoms include: rash, itching, redness, watery eyes and swelling.